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AGT

Gene

angiotensinogen

HGNCHGNC:333EnsemblENSG00000135744NCBI Gene183
Locus: gene with protein productLocation: 1q42.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSERPINA8
View full nomenclature history (3)
Previous symbolsSERPINA8
Previous namesserpin peptidase inhibitor, clade A, member 8
Alias namesalpha-1 antiproteinase, antitrypsin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Renal tubular dysgenesis
Renal tubular dysgenesis of genetic origin
Essential Hypertension
Hypertension
Cardiovascular Diseases
Essential hypertension, genetic
Atrial Fibrillation
Coronary Artery Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serpin peptidase inhibitorsNeuropeptides

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.