AGTR1

Gene

angiotensin II receptor type 1

HGNCHGNC:336 EnsemblENSG00000144891 NCBI Gene185

Locus: gene with protein productLocation: 3q24

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Type-1 angiotensin II receptorP30556

Protein · therapeutic target

Clinically validated target · 22 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAGTR1B · AT1 · AT2R1 · AGTR1A · AT2R1A · HAT1R · AG2S · AT2R1B · AT1B · ATR1

View full nomenclature history (12)

Previous symbolsAGTR1B

Alias symbolsAT1, AT2R1, AGTR1A, AT2R1A, HAT1R, AG2S, AT2R1B, AT1B, ATR1

Previous namesangiotensin receptor 1B

Alias namesangiotensin II type 1 receptor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Renal tubular dysgenesis

Hypertension

Renal tubular dysgenesis of genetic origin

Essential Hypertension

Heart Failure

Myocardial Infarction

Essential hypertension, genetic

Kidney Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Angiotensin receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.