ALG1

Gene

ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase

HGNCHGNC:18294 EnsemblENSG00000033011 NCBI Gene56052

Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHMT-1 · HMAT1 · CDG1K · Mat-1

View full nomenclature history (7)

Alias symbolsHMT-1, HMAT1, CDG1K, Mat-1

Previous namesasparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae), asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase), ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital disorder of glycosylation

Neurodegenerative Diseases

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glycosyl transferases group 1 domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.