ALG3

Gene

ALG3 alpha-1,3- mannosyltransferase

HGNCHGNC:23056 EnsemblENSG00000214160 NCBI Gene10195

Locus: gene with protein productLocation: 3q27.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNOT56L · Not56 · CDGS4 · D16Ertd36e

View full nomenclature history (9)

Alias symbolsNOT56L, Not56, CDGS4, D16Ertd36e

Previous namesasparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase), asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)

Alias namescarbohydrate deficient glycoprotein syndrome type IV, dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, dol-P-Man dependent alpha-1,3- mannosyltransferase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital disorder of glycosylation

Genetic Diseases, Inborn

Neurodegenerative Diseases

Neoplasms

Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Dolichyl D-mannosyl phosphate dependent mannosyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.