AR

Gene

androgen receptor

HGNCHGNC:644 EnsemblENSG00000169083 NCBI Gene367

Locus: gene with protein productLocation: Xq12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Androgen receptorP10275

Protein · therapeutic target

Clinically validated target · 19 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDHTR · SBMA · AIS · NR3C4 · SMAX1 · HUMARA

View full nomenclature history (10)

Previous symbolsDHTR, SBMA

Alias symbolsAIS, NR3C4, SMAX1, HUMARA

Previous namesdihydrotestosterone receptor, spinal and bulbar muscular atrophy

Alias namestesticular feminization, Kennedy disease

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Androgen insensitivity syndrome

Partial androgen insensitivity syndrome

Prostate adenocarcinoma

Familial prostate cancer

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nuclear receptor subfamily 3 group C

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.