ARNT

Gene

aryl hydrocarbon receptor nuclear translocator

HGNCHGNC:700 EnsemblENSG00000143437 NCBI Gene405

Locus: gene with protein productLocation: 1q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHIF-1beta · bHLHe2 · ARNT1

View full nomenclature history (4)

Alias symbolsHIF-1beta, bHLHe2, ARNT1

Alias nameshypoxia inducible factor 1 subunit beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Cutaneous melanoma

Carcinoma of liver and intrahepatic biliary tract

Carcinoma, Ductal, Breast

Hemangioblastoma

Alzheimer's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteinsPAS domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-13.

Open TargetsGene–disease associations from the Open Targets Platform.