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ARRB2

Gene

arrestin beta 2

HGNCHGNC:712EnsemblENSG00000141480NCBI Gene409
Locus: gene with protein productLocation: 17p13.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Beta-arrestin-2P32121

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asARR2 · BARR2 · DKFZp686L0365
View full nomenclature history (5)
Previous symbolsARR2
Alias symbolsBARR2, DKFZp686L0365
Previous namesarrestin, beta 2
Alias namesarrestin 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplasms
Noonan syndrome
Cardiomyopathy, Hypertrophic
Costello syndrome
Cardiofaciocutaneous syndrome
Lung carcinoma
Lung Neoplasms
Uterine Cervical Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Classical arrestins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.