Back to discover

ATP2B3

Gene

ATPase plasma membrane Ca2+ transporting 3

HGNCHGNC:816EnsemblENSG00000067842NCBI Gene492
Locus: gene with protein productLocation: Xq28

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCAX1 · CLA2 · PMCA3 · CFAP39
View full nomenclature history (9)
Previous symbolsSCAX1, CLA2
Alias symbolsPMCA3, CFAP39
Previous namesspinocerebellar ataxia, X-linked 1, cerebellar ataxia 2 (X-linked), ATPase, Ca++ transporting, plasma membrane 3
Alias namesplasma membrane calcium-transporting ATPase 3, cilia and flagella associated protein 39

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Adrenocortical Adenoma
Genetic Diseases, Inborn
Colonic Neoplasms
Colorectal adenocarcinoma
Cutaneous melanoma
HER2 positive breast carcinoma
Pancreatic Neoplasms
Skin squamous cell carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ATPases Ca2+ transportingCilia and flagella associated

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-10-11.
Open TargetsGene–disease associations from the Open Targets Platform.