AXIN1

Gene

axin 1

HGNCHGNC:903 EnsemblENSG00000103126 NCBI Gene8312

Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPPP1R49

View full nomenclature history (2)

Alias symbolsPPP1R49

Alias namesprotein phosphatase 1, regulatory subunit 49

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Hepatocellular

Neoplasms

Lung carcinoma

Prostate carcinoma

chronic myelogenous leukemia, BCR-ABL1 positive

Carcinoma of liver and intrahepatic biliary tract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.