BAP1

Gene

BRCA1 associated deubiquitinase 1

HGNCHGNC:950 EnsemblENSG00000163930 NCBI Gene8314

Locus: gene with protein productLocation: 3p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known ashucep-6 · KIAA0272 · UCHL2

View full nomenclature history (6)

Alias symbolshucep-6, KIAA0272, UCHL2

Previous namesBRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), BRCA1 associated protein 1

Alias namesubiquitin carboxy-terminal hydrolase L2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Uveal Melanoma

Carcinoma, Renal Cell

Neoplastic Syndromes, Hereditary

Inherited cancer-predisposing syndrome

Carcinoma, Hepatocellular

Neurodevelopmental Disorders

Cholangiocarcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ubiquitin C-terminal hydrolases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-07-04.

Open TargetsGene–disease associations from the Open Targets Platform.