BCL10

Gene

BCL10 immune signaling adaptor

HGNCHGNC:989 EnsemblENSG00000142867 NCBI Gene8915

Locus: gene with protein productLocation: 1p22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCARMEN · CIPER · mE10 · c-E10 · CLAP

View full nomenclature history (12)

Alias symbolsCARMEN, CIPER, mE10, c-E10, CLAP

Previous namesB cell CLL/lymphoma 10, BCL10, immune signaling adaptor

Alias namesCARD-like apoptotic protein, CARD-containing apoptotic signaling protein, CARD containing molecule enhancing NF-kB, caspase-recruiting domain-containing protein, CARD-containing proapoptotic protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoma, Follicular

Lymphoma, Large B-Cell, Diffuse

Mesothelioma

Lung carcinoma

Multiple Sclerosis

Carcinoma of liver and intrahepatic biliary tract

Colon carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Caspase recruitment domain containingCBM complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.