BCL6

Gene

BCL6 transcription repressor

HGNCHGNC:1001 EnsemblENSG00000113916 NCBI Gene604

Locus: gene with protein productLocation: 3q27.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

B-cell lymphoma 6 proteinP41182

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asZNF51 · ZBTB27 · LAZ3 · BCL5 · BCL6A

View full nomenclature history (8)

Previous symbolsZNF51

Alias symbolsZBTB27, LAZ3, BCL5, BCL6A

Previous nameszinc finger protein 51, B cell CLL/lymphoma 6, BCL6, transcription repressor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoma, Large B-Cell, Diffuse

Neurodegenerative Diseases

Colorectal adenocarcinoma

Skin squamous cell carcinoma

Hemangioblastoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.