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BIN1

Gene

bridging integrator 1

HGNCHGNC:1052EnsemblENSG00000136717NCBI Gene274
Locus: gene with protein productLocation: 2q14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAMPHL · SH3P9 · AMPH2
View full nomenclature history (6)
Previous symbolsAMPHL
Alias symbolsSH3P9, AMPH2
Alias namesamphiphysin II, amphiphysin 2, Myc box-dependent-interacting protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alzheimer's Disease
Dementia
Neurodegenerative Diseases
Lewy Body Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

N-BAR domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-04-21.
Open TargetsGene–disease associations from the Open Targets Platform.