Back to discover

BMPR2

Gene

bone morphogenetic protein receptor type 2

HGNCHGNC:1078EnsemblENSG00000204217NCBI Gene659
Locus: gene with protein productLocation: 2q33.1-q33.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPPH1 · BRK-3 · T-ALK · BMPR3 · BMPR-II
View full nomenclature history (8)
Previous symbolsPPH1
Alias symbolsBRK-3, T-ALK, BMPR3, BMPR-II
Previous namesbone morphogenetic protein receptor type II, bone morphogenetic protein receptor, type II (serine/threonine kinase), primary pulmonary hypertension 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Pulmonary arterial hypertension
Pulmonary Veno-Occlusive Disease
Idiopathic pulmonary arterial hypertension
Genetic non-acquired premature ovarian failure

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Type 2 receptor serine/threonine kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.