BSG

Gene

basigin (Ok blood group)

HGNCHGNC:1116 EnsemblENSG00000172270 NCBI Gene682

Locus: gene with protein productLocation: 19p13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

BasiginP35613

Protein · therapeutic target

Clinical-stage target · 1 candidate in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asOK · EMMPRIN · CD147 · EMPRIN

View full nomenclature history (8)

Previous symbolsOK

Alias symbolsEMMPRIN, CD147, EMPRIN

Previous namesbasigin

Alias namesOk blood group, extracellular matrix metalloproteinase inducer, Tumor cell-derived collagenase stimulatory factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Metabolism, Inborn Errors

Neurodegenerative Diseases

Graft vs Host Disease

Neoplasms

Carcinoma, Hepatocellular

Breast Neoplasms

Arthritis, Rheumatoid

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Blood group antigensCD moleculesI-set domain containingBasigin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.