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BUB1B

Gene

BUB1 mitotic checkpoint serine/threonine kinase B

HGNCHGNC:1149EnsemblENSG00000156970NCBI Gene701
Locus: gene with protein productLocation: 15q15.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBUBR1 · MAD3L · Bub1A · SSK1
View full nomenclature history (6)
Alias symbolsBUBR1, MAD3L, Bub1A, SSK1
Previous namesbudding uninhibited by benzimidazoles 1 (yeast homolog), beta, budding uninhibited by benzimidazoles 1 homolog beta (yeast)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Genetic Diseases, Inborn
Prostate carcinoma
Colon carcinoma
Carcinoma, Ductal, Breast
Gastric carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BUB1 mitotic checkpoint serine/threonine kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.