C4BPB

Gene

complement component 4 binding protein beta

HGNCHGNC:1328 EnsemblENSG00000123843 NCBI Gene725

Locus: gene with protein productLocation: 1q32.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC4BP

View full nomenclature history (4)

Previous symbolsC4BP

Previous namescomplement component 4-binding protein, beta

Alias namescomplement component 4 binding protein, beta chain, C4b binding protein, beta chain

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Venous Thromboembolism

Dengue

Neurodegenerative Diseases

Tuberculosis

Carcinoma, Hepatocellular

Barrett Esophagus

Major depressive disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sushi domain containingComplement system regulators and receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.