CA12

Gene

carbonic anhydrase 12

HGNCHGNC:1371 EnsemblENSG00000074410 NCBI Gene771

Locus: gene with protein productLocation: 15q22.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Carbonic anhydrase 12O43570

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Member of “Carbonic Anhydrases” · 1 related family paper (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHsT18816

View full nomenclature history (2)

Alias symbolsHsT18816

Previous namescarbonic anhydrase XII

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Isolated hyperchlorhidrosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Carbonic anhydrases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.