CACNA2D3

Gene

calcium voltage-gated channel auxiliary subunit alpha2delta 3

HGNCHGNC:15460 EnsemblENSG00000157445 NCBI Gene55799

Locus: gene with protein productLocation: 3p21.1-p14.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Voltage-dependent calcium channel subunit alpha-2/delta-3Q8IZS8

Protein · therapeutic target

Clinically validated target · 7 approved medicines against this target

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Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHSA272268 · alpha2delta-3

View full nomenclature history (4)

Alias symbolsHSA272268, alpha2delta-3

Previous namescalcium channel, voltage-dependent, alpha 2/delta subunit 3

Alias namesVoltage-dependent calcium channel subunit alpha-2/delta-3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Epilepsy

Anxiety Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Calcium voltage-gated channel auxiliary alpha2delta subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-31.

Open TargetsGene–disease associations from the Open Targets Platform.