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CAPN3

Gene

calpain 3

HGNCHGNC:1480EnsemblENSG00000092529NCBI Gene825
Locus: gene with protein productLocation: 15q15.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLGMD2 · LGMD2A · CANP3 · p94 · nCL-1
View full nomenclature history (5)
Previous symbolsLGMD2, LGMD2A
Alias symbolsCANP3, p94, nCL-1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Muscular dystrophy
Genetic Diseases, Inborn
Arrhythmias, Cardiac

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

EF-hand domain containingCalpains

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.