CAPZB

Gene

capping actin protein of muscle Z-line subunit beta

HGNCHGNC:1491 EnsemblENSG00000077549 NCBI Gene832

Locus: gene with protein productLocation: 1p36.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (3)

Previous namescapping protein (actin filament) muscle Z-line, beta, capping actin protein of muscle Z-line beta subunit

Alias namesCapZ beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Dynactin subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-31.

Open TargetsGene–disease associations from the Open Targets Platform.