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CBFA2T3

Gene

CBFA2/RUNX1 partner transcriptional co-repressor 3

HGNCHGNC:1537EnsemblENSG00000129993NCBI Gene863
Locus: gene with protein productLocation: 16q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTGR2 · ZMYND4 · MTG16 · RUNX1T3 · ETO2
View full nomenclature history (8)
Alias symbolsMTGR2, ZMYND4, MTG16, RUNX1T3, ETO2
Previous namescore-binding factor, runt domain, alpha subunit 2; translocated to, 3, CBFA2/RUNX1 translocation partner 3
Alias namesmyeloid translocation gene 8 and 16b

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Myeloproliferative disorder
Leukemia, Myeloid, Acute
Lung carcinoma
Carcinoma, Pancreatic Ductal
Carcinoma, Ductal, Breast
Thyroid tumor
Lymphoid neoplasm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers MYND-typeA-kinase anchoring proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.