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CBL

Gene

Cbl proto-oncogene

HGNCHGNC:1541EnsemblENSG00000110395NCBI Gene867
Locus: gene with protein productLocation: 11q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCBL2 · RNF55 · c-Cbl
View full nomenclature history (6)
Previous symbolsCBL2
Alias symbolsRNF55, c-Cbl
Previous namesCas-Br-M (murine) ecotropic retroviral transforming sequence, Cbl proto-oncogene, E3 ubiquitin protein ligase
Alias namesoncogene CBL2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Noonan syndrome
RASopathy
Listeriosis
Neoplasms
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-09-23.
Open TargetsGene–disease associations from the Open Targets Platform.