CCND1

Gene

cyclin D1

HGNCHGNC:1582 EnsemblENSG00000110092 NCBI Gene595

Locus: gene with protein productLocation: 11q13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

G1/S-specific cyclin-D1P24385

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Member of “Cyclins” · 3 related family papers (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBCL1 · D11S287E · PRAD1 · U21B31

View full nomenclature history (8)

Previous symbolsBCL1, D11S287E, PRAD1

Alias symbolsU21B31

Previous namescyclin D1 (PRAD1: parathyroid adenomatosis 1)

Alias namesparathyroid adenomatosis 1, B-cell CLL/lymphoma 1, G1/S-specific cyclin D1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Breast Neoplasms

Multiple Myeloma

Neurodegenerative Diseases

Prostate carcinoma

Immunoglobulin Light-chain Amyloidosis

Diabetes Mellitus, Type 2

Neoplasms

Diabetes Mellitus

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cyclins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.