CD247

Gene

CD247 molecule

HGNCHGNC:1677 EnsemblENSG00000198821 NCBI Gene919

Locus: gene with protein productLocation: 1q24.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD3Z · CD3H · CD3Q · TCRZ · CD3-ZETA · CD3ZETA

View full nomenclature history (9)

Previous symbolsCD3Z

Alias symbolsCD3H, CD3Q, TCRZ, CD3-ZETA, CD3ZETA

Previous namesCD3z antigen, zeta polypeptide (TiT3 complex), CD247 antigen

Alias namesT-cell surface glycoprotein CD3 zeta chain

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leishmaniasis, Cutaneous

Asthma

T-B- severe combined immunodeficiency

Hypothyroidism

Rhinitis, Allergic

Hypersensitivity

Respiratory Tract Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.