CD79B

Gene

CD79b molecule

HGNCHGNC:1699 EnsemblENSG00000007312 NCBI Gene974

Locus: gene with protein productLocation: 17q23.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

B-cell antigen receptor complex-associated protein beta chainP40259

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIGB · B29 · Ig-beta · Igbeta

View full nomenclature history (7)

Previous symbolsIGB

Alias symbolsB29, Ig-beta, Igbeta

Previous namesCD79B antigen (immunoglobulin-associated beta), CD79b molecule, immunoglobulin-associated beta

Alias namesB-cell antigen receptor complex-associated protein beta chain

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoma, Large B-Cell, Diffuse

Isolated agammaglobulinemia

Autosomal agammaglobulinemia

Agammaglobulinemia

B-cell non-Hodgkin's lymphoma

Neoplasms

diffuse large B-cell lymphoma of the central nervous system

Primary central nervous system lymphoma

breast diffuse large B-cell lymphoma

Lymphoid neoplasm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesV-set domain containingCD79 molecule family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.