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CDKN1B

Gene

cyclin dependent kinase inhibitor 1B

HGNCHGNC:1785EnsemblENSG00000111276NCBI Gene1027
Locus: gene with protein productLocation: 12p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIP1 · P27KIP1
View full nomenclature history (3)
Alias symbolsKIP1, P27KIP1
Previous namescyclin-dependent kinase inhibitor 1B (p27, Kip1)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Prostate carcinoma
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Thyroid gland carcinoma
Neurodegenerative Diseases
Thyroid Neoplasms
Diabetes Mellitus, Type 2
Prostate adenocarcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cyclin dependent kinase inhibitor 1 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.