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CERS1

Gene

ceramide synthase 1

HGNCHGNC:14253EnsemblENSG00000223802NCBI Gene10715
Locus: gene with protein productLocation: 19p13.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLASS1 · LAG1 · UOG1
View full nomenclature history (6)
Previous symbolsLASS1
Alias symbolsLAG1, UOG1
Previous nameslongevity assurance (LAG1, S. cerevisiae) homolog 1, LAG1 longevity assurance homolog 1 (S. cerevisiae), LAG1 homolog, ceramide synthase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Heterotaxia
Visceral heterotaxy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ceramide synthases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.