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CFB

Gene

complement factor B

HGNCHGNC:1037EnsemblENSG00000243649NCBI Gene629
Locus: gene with protein productLocation: 6p21.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBFD · BF · H2-Bf
View full nomenclature history (6)
Previous symbolsBFD, BF
Alias symbolsH2-Bf
Previous namesB-factor, properdin
Alias namesproperdin B, properdin factor B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glomerulonephritis, IGA

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine proteasesSushi domain containingComplement system activation components

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-08-02.
Open TargetsGene–disease associations from the Open Targets Platform.