Back to discover

CFH

Gene

complement factor H

HGNCHGNC:4883EnsemblENSG00000000971NCBI Gene3075
Locus: gene with protein productLocation: 1q31.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHF · HF1 · HF2 · HUS · FHL1 · ARMS1 · ARMD4
View full nomenclature history (11)
Previous symbolsHF, HF1, HF2
Alias symbolsHUS, FHL1, ARMS1, ARMD4
Previous namesH factor 1 (complement)
Alias namesbeta-1H, H factor 2 (complement), age-related maculopathy susceptibility 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Macular Degeneration
Retinal Diseases
Wet macular degeneration

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sushi domain containingComplement system regulators and receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.