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CHRNA1

Gene

cholinergic receptor nicotinic alpha 1 subunit

HGNCHGNC:1955EnsemblENSG00000138435NCBI Gene1134
Locus: gene with protein productLocation: 2q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCHRNA
View full nomenclature history (5)
Previous symbolsCHRNA
Previous namescholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), cholinergic receptor, nicotinic, alpha 1 (muscle), cholinergic receptor, nicotinic alpha 1
Alias namesacetylcholine receptor, nicotinic, alpha 1 (muscle)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital myasthenic syndromes

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cholinergic receptors nicotinic subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-08-03.
Open TargetsGene–disease associations from the Open Targets Platform.