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CHRNA5

Gene

cholinergic receptor nicotinic alpha 5 subunit

HGNCHGNC:1959EnsemblENSG00000169684NCBI Gene1138
Locus: gene with protein productLocation: 15q25.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (4)
Previous namescholinergic receptor, nicotinic, alpha polypeptide 5, cholinergic receptor, nicotinic, alpha 5 (neuronal), cholinergic receptor, nicotinic alpha 5
Alias namesacetylcholine receptor, nicotinic, alpha 5 (neuronal)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lung carcinoma
Pulmonary Disease, Chronic Obstructive
Lung Neoplasms
Adenocarcinoma of Lung
Chronic bronchitis
Atherosclerosis
Pulmonary Emphysema
Respiratory Insufficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cholinergic receptors nicotinic subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.