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CIRSR

Gene

corepressor of RBPJ and splicing regulator

HGNCHGNC:24217EnsemblENSG00000138433NCBI Gene9541
Locus: gene with protein productLocation: 2q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCIR1 · CIR
View full nomenclature history (7)
Previous symbolsCIR1
Alias symbolsCIR
Previous namescorepressor interacting with RBPJ, 1, CBF1 (RBPJ) interacting corepressor 1, corepressor interacting with RBPJ, CIR1
Alias namesrecepin, CBF1 interacting corepressor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Major depressive disorder
Diabetes Mellitus
Diabetes Mellitus, Type 2
Noonan syndrome
Fanconi Anemia
Noonan syndrome with multiple lentigines

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-03-19.
Open TargetsGene–disease associations from the Open Targets Platform.