CISD2

Gene

CDGSH iron sulfur domain 2

HGNCHGNC:24212 EnsemblENSG00000145354 NCBI Gene493856

Locus: gene with protein productLocation: 4q24

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asZCD2 · WFS2 · Miner1 · ERIS · NAF-1

View full nomenclature history (10)

Previous symbolsZCD2, WFS2

Alias symbolsMiner1, ERIS, NAF-1

Previous nameszinc finger, CDGSH-type domain 2, Wolfram syndrome 2

Alias namesmitoNEET related 1, endoplasmic reticulum intermembrane small protein, nutrient-deprivation autophagy factor-1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Genetic Diseases, Inborn

Diabetes Mellitus, Type 1

Diabetes Mellitus

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CDGSH iron sulfur domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.