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CLCN7

Gene

Cl-/H+ antiporter 7

HGNCHGNC:2025EnsemblENSG00000103249NCBI Gene1186
Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCLC-7 · OPTA2 · CLC7 · PPP1R63
View full nomenclature history (8)
Alias symbolsCLC-7, OPTA2, CLC7, PPP1R63
Previous nameschloride voltage-gated channel 7, chloride channel 7, chloride channel, voltage-sensitive 7
Alias namesprotein phosphatase 1, regulatory subunit 63

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Bone Diseases
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CLC chloride channel and transporter familyProtein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-20.
Open TargetsGene–disease associations from the Open Targets Platform.