CNKSR1

Gene

connector enhancer of kinase suppressor of Ras 1

HGNCHGNC:19700 EnsemblENSG00000142675 NCBI Gene10256

Locus: gene with protein productLocation: 1p36.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCNK1 · KSR · CNK

View full nomenclature history (3)

Alias symbolsCNK1, KSR, CNK

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplasms

Noonan syndrome

Cardiomyopathy, Hypertrophic

Costello syndrome

Cardiofaciocutaneous syndrome

Autoimmune disorder of central nervous system

Neurodevelopmental Disorders

Pancreatic Neoplasms

Gout

Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containingSterile alpha motif domain containingPDZ domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.