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COPS5

Gene

COP9 signalosome subunit 5

HGNCHGNC:2240EnsemblENSG00000121022NCBI Gene10987
Locus: gene with protein productLocation: 8q13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asJAB1 · SGN5 · MOV-34 · CSN5
View full nomenclature history (6)
Alias symbolsJAB1, SGN5, MOV-34, CSN5
Previous namesCOP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Genetic Diseases, Inborn
Neoplasms
Carcinoma, Hepatocellular
Nasopharyngeal Carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

COP9 signalosomeJAMM/MPN+ metallopeptidase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.