COXFA4

Gene

cytochrome c oxidase associated subunit FA4

HGNCHGNC:7687 EnsemblENSG00000189043 NCBI Gene4697

Locus: gene with protein productLocation: 7p21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNDUFA4 · MLRQ · CI-9k · MRCAF1 · MISTR1

View full nomenclature history (13)

Previous symbolsNDUFA4

Alias symbolsMLRQ, CI-9k, MRCAF1, MISTR1

Previous namesNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9kD, MLRQ), NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa, NDUFA4 mitochondrial complex associated

Alias namescomplex I 9kDa subunit, NADH-ubiquinone oxidoreductase MLRQ subunit, cytochrome c oxidase subunit FA4, mitochondrial respiratory chain associated factor 1, mitochondrial stress response 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Diabetes Mellitus

Diabetes Mellitus, Type 1

Pre-Eclampsia

Metabolic Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial complex IV: cytochrome c oxidase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-07-07.

Open TargetsGene–disease associations from the Open Targets Platform.