CPAP

Gene

centrosome assembly and centriole elongation protein

HGNCHGNC:17272 EnsemblENSG00000151849 NCBI Gene55835

Locus: gene with protein productLocation: 13q12.12-q12.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCENPJ · MCPH6 · LAP · LIP1 · BM032 · SASS4 · SCKL4 · Sas-4

View full nomenclature history (14)

Previous symbolsCENPJ, MCPH6

Alias symbolsLAP, LIP1, BM032, SASS4, SCKL4, Sas-4

Previous namescentromere protein J, microcephaly, primary autosomal recessive 6

Alias namescentrosomal P4.1-associated protein, Seckel syndrome 4, Spindle assembly abnormal 4, LAG-3-associated protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autosomal recessive primary microcephaly

Seckel syndrome

Microcephaly 1, primary, autosomal recessive

Lissencephaly type 3

Genetic Diseases, Inborn

Microcephalic primordial dwarfism

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-10-25.

Open TargetsGene–disease associations from the Open Targets Platform.