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CYP27A1

Gene

cytochrome P450 family 27 subfamily A member 1

HGNCHGNC:2605EnsemblENSG00000135929NCBI Gene1593
Locus: gene with protein productLocation: 2q35

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP27 · CTX · CP27
View full nomenclature history (6)
Previous symbolsCYP27
Alias symbolsCTX, CP27
Previous namescytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1, cytochrome P450, family 27, subfamily A, polypeptide 1
Alias namescerebrotendinous xanthomatosis

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cerebrotendinous xanthomatosis
Placental retention
Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 27

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.
Open TargetsGene–disease associations from the Open Targets Platform.