CYP2B6

Gene

cytochrome P450 family 2 subfamily B member 6

HGNCHGNC:2615 EnsemblENSG00000197408 NCBI Gene1555

Locus: gene with protein productLocation: 19q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP2B · CPB6 · CYPIIB6

View full nomenclature history (7)

Previous symbolsCYP2B

Alias symbolsCPB6, CYPIIB6

Previous namescytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6, cytochrome P450, family 2, subfamily B, cytochrome P450, subfamily IIB (phenobarbital-inducible), cytochrome P450, family 2, subfamily B, polypeptide 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Mastocytosis

Cutaneous mastocytosis

Osteoarthritis

Parkinson's Disease

Nasal Polyps

Leukemia, Myeloid, Acute

Neoplasms

Obesity due to melanocortin 4 receptor deficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 2

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.

Open TargetsGene–disease associations from the Open Targets Platform.