CYP7A1

Gene

cytochrome P450 family 7 subfamily A member 1

HGNCHGNC:2651 EnsemblENSG00000167910 NCBI Gene1581

Locus: gene with protein productLocation: 8q12.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Cytochrome P450 7A1P22680

Protein · therapeutic target

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Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP7

View full nomenclature history (5)

Previous symbolsCYP7

Previous namescytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1, cytochrome P450, family 7, subfamily A, polypeptide 1

Alias namescholesterol 7 alpha-monooxygenase, cholesterol 7α-hydroxylase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 7

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.