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DDX10

Gene

DEAD-box helicase 10

HGNCHGNC:2735EnsemblENSG00000178105NCBI Gene1662
Locus: gene with protein productLocation: 11q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHRH-J8 · Dbp4
View full nomenclature history (4)
Alias symbolsHRH-J8, Dbp4
Previous namesDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase), DEAD (Asp-Glu-Ala-Asp) box polypeptide 10

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Lymphoid neoplasm
Carcinoma of liver and intrahepatic biliary tract
Carcinoma, Ductal, Breast
Carcinoma, Pancreatic Ductal
Gastric carcinoma
HER2 positive breast carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DEAD-box helicasesSSU processome

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-11-07.
Open TargetsGene–disease associations from the Open Targets Platform.