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DDX42

Gene

DEAD-box helicase 42

HGNCHGNC:18676EnsemblENSG00000198231NCBI Gene11325
Locus: gene with protein productLocation: 17q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRNAHP · RHELP · SF3b125 · SF3B8
View full nomenclature history (7)
Alias symbolsRNAHP, RHELP, SF3b125, SF3B8
Previous namesDEAD (Asp-Glu-Ala-Asp) box polypeptide 42, DEAD (Asp-Glu-Ala-Asp) box helicase 42
Alias namessplicing factor 3b, subunit 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dengue
Neurodegenerative Diseases
Carcinoma, Hepatocellular
Atrial Fibrillation
Pre-Eclampsia
Familial gestational hyperthyroidism

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DEAD-box helicases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.