DERL1

Gene

derlin 1

HGNCHGNC:28454 EnsemblENSG00000136986 NCBI Gene79139

Locus: gene with protein productLocation: 8q24.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRO2577 · DER1 · DER-1 · derlin-1 · MGC3067 · FLJ13784

View full nomenclature history (7)

Alias symbolsPRO2577, DER1, DER-1, derlin-1, MGC3067, FLJ13784

Previous namesDer1-like domain family, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cystic Fibrosis

Response to antihypertensive drug

Urinary bladder carcinoma

Urinary Bladder Neoplasms

Neoplasms

Carcinoma, Hepatocellular

Arthritis, Rheumatoid

Squamous Cell Carcinoma of Head and Neck

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Rhomboid family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.