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DERL3

Gene

derlin 3

HGNCHGNC:14236EnsemblENSG00000099958NCBI Gene91319
Locus: gene with protein productLocation: 22q11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC22orf14 · FLJ43842 · MGC71803 · derlin-3 · IZP6
View full nomenclature history (7)
Previous symbolsC22orf14
Alias symbolsFLJ43842, MGC71803, derlin-3, IZP6
Previous nameschromosome 22 open reading frame 14, Der1-like domain family, member 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cystic Fibrosis
Atrial Fibrillation
Cardiomyopathy, Hypertrophic
Heart Failure
Heart Failure, Systolic
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Rhomboid family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.