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DES

Gene

desmin

HGNCHGNC:2770EnsemblENSG00000175084NCBI Gene1674
Locus: gene with protein productLocation: 2q35

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMD1I · CSM1 · CSM2 · LGMD2R
View full nomenclature history (6)
Alias symbolsCMD1I, CSM1, CSM2, LGMD2R
Alias namesintermediate filament protein, cardiomyopathy, dilated 1I

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial isolated dilated cardiomyopathy
Cardiomyopathy, Dilated
Cardiomyopathies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Intermediate filaments Type III

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-09-04.
Open TargetsGene–disease associations from the Open Targets Platform.