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DESI2

Gene

desumoylating isopeptidase 2

HGNCHGNC:24264EnsemblENSG00000121644NCBI Gene51029
Locus: gene with protein productLocation: 1q44

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC1orf121 · FAM152A · PPPDE1 · CGI-146 · FLJ21998 · PNAS-4 · DESI-2
View full nomenclature history (10)
Previous symbolsC1orf121, FAM152A, PPPDE1
Alias symbolsCGI-146, FLJ21998, PNAS-4, DESI-2
Previous nameschromosome 1 open reading frame 121, PPPDE peptidase domain containing 1, family with sequence similarity 152, member A

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gastrointestinal Diseases
Brain Diseases
Response to antihypertensive drug
Neoplasms
Carcinoma, Pancreatic Ductal
Respiratory Tract Infections
Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Desumoylating isopeptidases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.