DET1

Gene

DET1 partner of COP1 E3 ubiquitin ligase

HGNCHGNC:25477 EnsemblENSG00000140543 NCBI Gene55070

Locus: gene with protein productLocation: 15q26.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFLJ10103

View full nomenclature history (3)

Alias symbolsFLJ10103

Previous namesde-etiolated homolog 1 (Arabidopsis), DET1, COP1 ubiquitin ligase partner

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hyperthyroidism

Thyroid Diseases

Dental Caries

Neurodegenerative Diseases

Hashimoto's Disease

Hypothyroidism

Pulmonary Disease, Chronic Obstructive

Insulinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.