DGCR8

Gene

DGCR8 microprocessor complex subunit

HGNCHGNC:2847 EnsemblENSG00000128191 NCBI Gene54487

Locus: gene with protein productLocation: 22q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC22orf12 · DGCRK6 · Gy1 · pasha

View full nomenclature history (7)

Previous symbolsC22orf12

Alias symbolsDGCRK6, Gy1, pasha

Previous nameschromosome 22 open reading frame 12, DGCR8, microprocessor complex subunit, DiGeorge syndrome critical region gene 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Wilms Tumor

Smoking initiation

Lymphoma, Large B-Cell, Diffuse

Squamous Cell Carcinoma of Head and Neck

Carcinoma, Hepatocellular

Neoplasms

Leukemia, Myeloid, Acute

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesMicroprocessor complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-01-26.

Open TargetsGene–disease associations from the Open Targets Platform.